Growth-hormone-releasing hormone analogue

CJC-1295

Also known as: Modified GRF (1-29) · CJC-1295 without DAC

A GHRH analogue studied for its effect on growth-hormone release, often researched alongside a ghrelin-mimetic.

Overview

CJC-1295 is a synthetic analogue of growth-hormone-releasing hormone (GHRH). The "without DAC" form (modified GRF 1-29) has a short action and is frequently studied in combination with a ghrelin-receptor agonist such as Ipamorelin. A DAC-modified version was investigated for a much longer half-life.

How it’s studied to work

As a GHRH analogue it binds GHRH receptors on the pituitary to stimulate the synthesis and pulsatile release of growth hormone, complementing the separate ghrelin-receptor pathway.

Research areas

  • Growth-hormone and IGF-1 axis research
  • Pulsatile GH secretion
  • Secretagogue combination studies

Handling & storage

Storage
Lyophilized; store cold, long-term at −20 °C.
Reconstitution
Bacteriostatic water for laboratory reconstitution.

Further reading

Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.

For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.