Ibutamoren
Also known as: MK-677 · MK-0677
A non-peptide, orally active growth-hormone secretagogue used widely as a research tool.
Overview
Ibutamoren (MK-677) is a non-peptide compound that mimics ghrelin at its receptor and is orally bioavailable — unusual among secretagogues. It has appeared in clinical research on the GH/IGF-1 axis and body composition.
How it’s studied to work
It is a potent agonist of the growth-hormone secretagogue receptor (GHS-R1a), increasing GH and IGF-1 in research settings while being active by the oral route.
Research areas
- ›Growth-hormone / IGF-1 elevation
- ›Body-composition and bone research
- ›Sleep and appetite signalling
Further reading
Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.
For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.
