Decapeptide reproductive-axis signal

Kisspeptin-10

Also known as: KP-10 · Metastin fragment

A key upstream signal of the reproductive hormone axis, studied in fertility and endocrine research.

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Overview

Kisspeptin-10 is the shortest active fragment of kisspeptin, a peptide that sits near the top of the hypothalamic-pituitary-gonadal (HPG) axis. It has an active human clinical-research literature in reproductive endocrinology.

How it’s studied to work

Kisspeptin binds the KISS1R (GPR54) receptor on hypothalamic neurons to stimulate release of gonadotropin-releasing hormone (GnRH), the master trigger of the downstream reproductive-hormone cascade.

Research areas

  • Reproductive-axis (HPG) regulation
  • GnRH / gonadotropin release
  • Fertility and puberty research

Handling & storage

Storage
Lyophilized; store cold.
Reconstitution
Bacteriostatic water for laboratory reconstitution.

Further reading

Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.

For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.