KPV
Also known as: Lysine-Proline-Valine · α-MSH(11-13)
A short tripeptide fragment of α-MSH investigated for anti-inflammatory activity in the gut and skin.
Overview
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (α-MSH). Unlike the parent hormone it lacks pigmentary activity, and research focuses on its reported anti-inflammatory properties in gastrointestinal and dermatological models.
How it’s studied to work
KPV is studied for its ability to enter cells and interfere with pro-inflammatory signalling (including NF-κB and pro-inflammatory cytokine pathways), independent of melanocortin-receptor pigmentation effects.
Research areas
- ›Intestinal inflammation models (e.g. colitis)
- ›Skin inflammation and barrier research
- ›NF-κB / cytokine signalling
Handling & storage
- Storage
- Lyophilized; store cold.
- Reconstitution
- Bacteriostatic water for laboratory reconstitution.
Further reading
Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.
For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.