Melanocortin-receptor agonist

PT-141

Also known as: Bremelanotide

A melanocortin-receptor agonist studied for effects on sexual-response pathways in the nervous system.

Overview

PT-141 (bremelanotide) is a cyclic peptide derived from the melanocortin system and related to Melanotan II, but researched primarily for central sexual-response endpoints rather than pigmentation.

How it’s studied to work

It is studied as an agonist at melanocortin receptors (notably MC4R) in the central nervous system, a pathway implicated in sexual arousal signalling — distinct from vascular mechanisms.

Research areas

  • Melanocortin (MC4R) signalling
  • Central sexual-response research

Further reading

Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.

For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.