Growth-hormone-releasing hormone analogue

Sermorelin

Also known as: GRF (1-29) · GHRH (1-29)

The 1-29 fragment of GHRH — the shortest sequence retaining full GH-releasing activity in research.

Overview

Sermorelin corresponds to the first 29 amino acids of growth-hormone-releasing hormone, the minimal fragment that retains its biological activity. It has a long history as a research and diagnostic agent for probing the GH axis.

How it’s studied to work

It binds pituitary GHRH receptors to stimulate endogenous growth-hormone production, preserving the body’s own feedback regulation of the axis.

Research areas

  • GH-axis and pituitary-function research
  • Diagnostic GH-stimulation studies
  • IGF-1 response modelling

Further reading

Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.

For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.