Actin-binding peptide (Tβ4-derived)

TB-500

Also known as: Thymosin Beta-4 fragment · TB4

A synthetic peptide related to Thymosin Beta-4, studied for cell migration and tissue-repair processes.

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Overview

TB-500 is a synthetic peptide corresponding to an active region of Thymosin Beta-4 (Tβ4), a naturally occurring protein involved in cytoskeletal regulation. Research interest centres on wound-healing and regenerative endpoints in animal and cell models.

How it’s studied to work

Tβ4 is a major regulator of actin, the protein that builds the cellular cytoskeleton. By sequestering actin monomers, it is studied for its role in cell migration, angiogenesis, and the reorganisation that accompanies tissue repair.

Research areas

  • Actin regulation and cell migration
  • Wound healing and tissue remodelling (preclinical)
  • Cardiac and corneal repair models
  • Anti-inflammatory signalling

Handling & storage

Storage
Lyophilized; store cold, long-term at −20 °C.
Reconstitution
Bacteriostatic water for laboratory reconstitution.

Further reading

Links open external literature databases. Citations are curated starting points, not an exhaustive or endorsing list.

For laboratory and research use only. Not a drug, supplement, or medical device. This page is educational and is not medical advice; nothing here describes a product intended for human or veterinary use.